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    Noncoplanar PCBs, with chlorine atoms at the ortho positions can cause neurotoxic and immunotoxic effects, but only at concentrations much higher than those normally associated with dioxins.They do not activate the Ah R, and are not considered part of the dioxin group.In an electric arc, PCBs generate incombustible gases.Use of PCBs is commonly divided into closed and open applications.Other physical and chemical properties vary widely across the class.As the degree of chlorination increases, melting point and lipophilicity increase, and vapour pressure and water solubility decrease.Because of PCBs' environmental toxicity and classification as a persistent organic pollutant, PCB production was banned by the United States Congress in 1979 and by the Stockholm Convention on Persistent Organic Pollutants in 2001. Environmental Protection Agency (EPA), PCBs cause cancer in animals and are probable human carcinogens.

    The maximum allowable contaminant level in drinking water in the United States is set at zero, but because of the limitations of water treatment technologies, a level of 0.5 parts per billion is the de facto level.PCBs have entered the environment through both use and disposal.The environmental fate of PCBs is complex and global in scale.It is unlikely that a full inventory of global PCB production will ever be accurately tallied, as there were factories in Poland, East Germany, and Austria that produced unknown amounts of PCBs.The utility of PCBs is based largely on their chemical stability, including low flammability and high dielectric constant.

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